DocumentCode
2471498
Title
Design and assembly of a sterile nanoscale orthopedic biomaterial
Author
Longsworth, John ; Eppell, Steven
Author_Institution
Dept. of Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA
fYear
2002
fDate
2002
Firstpage
173
Lastpage
174
Abstract
This paper details the design and manufacture of a synthetic biomimetic bone biomaterial. The material is a composite of collagen fibrils and nanometer sized mineral apatites to enhance its resorbability over previous hydroxyapatite ceramics and bone cements. An aseptic protocol for producing a sterile composite has been developed and tested. It is now possible to use this biomaterial in cell experiments
Keywords
biomedical materials; biomimetics; bone; composite materials; nanostructured materials; orthopaedics; proteins; self-assembly; aseptic protocol; biomimetic bone biomaterial; bone healing; collagen fibrils; collagen scaffold; composite biomaterial; nanometer sized mineral apatites; osteoclast cell cultures; resorbability; self-assembly protocol; sterile nanoscale orthopedic biomaterial; triple helical monomers; trypsin digestion; Assembly; Biological materials; Biomimetics; Bones; Building materials; Ceramics; Composite materials; Minerals; Orthopedic surgery; Pulp manufacturing;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast
Conference_Location
Philadelphia, PA
Print_ISBN
0-7803-7419-3
Type
conf
DOI
10.1109/NEBC.2002.999521
Filename
999521
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