High aspect-ratio microchip-based capillary electrophoresis device using chemically machinable photosensitive glass substrate

To analyze DNA fragments rapidly and easily will be a most important process in a future DNA industry. This paper reports a new fabrication process and a new device structure for microchip-based capillary electrophoresis (CE) using chemically machinable photosensitive glass substrate. The fabrication process of our device has an advantage in mass production as an inexpensive device. In addition we can easily obtain the high aspect-ratio structure of the channel, which presents high performance in separation characteristics.