9B-3 Orthogonal Observations of Vibrating Microbubbles

Phospholipids-coated microbubbles nearby a wall can achieve strong nonspherical oscillations. This proceeding quantifies these oscillations at conditions relevant to clinical ultrasound contrast imaging. The experimental setup consisted of two microscope objectives placed orthogonally, one giving a top- view of a single microbubble floating up to a wall, the second giving a side-view of the very same bubble. The bubble was excited with ultrasound pulses of 2.25 MHz frequency and increasing pressures from 30 to 300 kPa. Images from the two objectives were combined and relayed to the ultrafast-framing Brandaris-128 camera. Analysis of the clips shows nonspherical shapes that are described by the spherical harmonic of the 2deg degree, having oscillation amplitude of the order of the radial oscillations.