Fading spectrophotometric method for the determination of Benzbromarone with Cresol Red

Author

Deng, Gaowa-Ao ; Jin, Yingchun ; An, Na

Author_Institution

Coll. of Chem. & Chem. Eng., Inner Mongolia Univ., Hohhot, China

fYear

2011

fDate

24-26 June 2011

Firstpage

6853

Lastpage

6855

Abstract

In pH 9.00 tris-HCl buffer medium, Cresol Red reacted with Benzbromarone to form an ion association complex, which causes the fading of the Cresol Red solution.The results showed that the maximum fading wavelength is located at 569.0nm. The concentration of BM obeyed the Beer´s law in the range of 0.09874~22.22μg·mL^-1 and the regression equation was ΔA=0.0972c-0.0245 (c=μg/mL) with the correlation coefficient was 0.9997, the apparent molar absorptivity was 3.978×10⁴ L·mol^-1·cm^-1. Fading spectrophotometric method has been developed for the determination of medicinal preparation and biological samples with Benzbromarone. The recovery of sample was within the the range of 96.31~99.11%.

Keywords

association; biochemistry; biomedical materials; dyes; spectrochemical analysis; spectrophotometry; Beer law; Cresol Red solution; benzbromarone; biological samples; correlation coefficient; fading spectrophotometric method; ion association complex; medicinal preparation; molar absorptivity; regression equation; Blood; Chemical engineering; Equations; Fading; Kidney; Neodymium; Benzbromarone; Cresol Red; Fading spectrophotometric method;

fLanguage

English

Publisher

ieee

Conference_Titel

Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on

Conference_Location

Nanjing

Print_ISBN

978-1-4244-9172-8

Type

conf

DOI

10.1109/RSETE.2011.5965938

Filename

5965938