Title :
Assessment of bradykinesia in Parkinson´s disease patients through a multi-parametric system
Author :
Pastorino, M. ; Cancela, J. ; Arredondo, M.T. ; Pansera, M. ; Pastor-Sanz, L. ; Villagra, F. ; Pastor, M.A. ; Martín, J.A.
Author_Institution :
Life Supporting Technol., Tech. Univ. of Madrid (UPM), Madrid, Spain
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
The aim of this paper is to describe and present the results of the automatic detection and assessment of bradykinesia in motor disease patients using wireless, wearable accelerometers. The current work is related to a module of the PERFORM system, a FP7 project from the European Commission, that aims at providing an innovative and reliable tool, able to evaluate, monitor and manage patients suffering from Parkinson´s disease. The assessment procedure was carried out through a developed C# library that detects the activities of the patient using an activity recognition algorithm and classifies the data using a Support Vector Machine trained with data coming from previous test phases. The accuracy between the output of the automatic detection and the evaluation of the clinician both expressed with the Unified Parkinson´s disease Rating Scale, presents an average value of [68.3±8.9]%. A meta-analysis algorithm is used in order to improve the accuracy to an average value of [74.4±14.9]%. Future work will include a personalized training of the classifiers in order to achieve a higher level of accuracy.
Keywords :
accelerometers; biomechanics; biomedical equipment; diseases; patient monitoring; support vector machines; PERFORM system; Parkinson disease; activity recognition algorithm; automatic detection; bradykinesia; metaanalysis algorithm; motor disease patients; multiparametric system; support vector machine; wearable accelerometers; wireless accelerometer; Accuracy; Basal ganglia; Classification algorithms; Educational institutions; Feature extraction; Parkinson´s disease; Protocols; Actigraphy; Adult; Aged; Diagnosis, Computer-Assisted; Equipment Design; Equipment Failure Analysis; Female; Humans; Hypokinesia; Male; Middle Aged; Monitoring, Ambulatory; Parkinson Disease; Reproducibility of Results; Sensitivity and Specificity; Support Vector Machines; Telemetry;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6090516