Title :
Chronic stimulation of the semicircular canals using a multichannel vestibular prosthesis: Effects on locomotion and angular vestibulo-ocular reflex in chinchillas
Author :
Sun, Daniel Q. ; Rahman, Mehdi A. ; Fridman, Gene ; Dai, Chenkai ; Chiang, Bryce ; Della Santina, Charles C.
Author_Institution :
Sch. of Med., Dept. of Otolaryngology-Head & Neck Surg., Johns Hopkins Univ., Baltimore, MD, USA
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
Bilateral loss of vestibular sensation causes difficulty maintaining stable vision, posture and gait. An implantable prosthesis that partly restores vestibular sensation could significantly improve quality of life for individuals disabled by this disorder. We have developed a head-mounted multichannel vestibular prosthesis (MVP) that restores sufficient semicircular canal function to recreate a 3D angular vestibulo-ocular reflex (aVOR). In this study, we evaluated effects of chronic MVP stimulation on locomotion in chinchillas. Two of three animals examined exhibited significant improvements in both locomotion and aVOR.
Keywords :
prosthetics; 3D angular vestibulo-ocular reflex; bilateral loss; chinchillas; chronic MVP stimulation; chronic stimulation; head-mounted multichannel vestibular prosthesis; implantable prosthesis; locomotion; semicircular canal function; vestibular sensation; Animals; Frequency modulation; Head; Irrigation; Prosthetics; Three dimensional displays; Animals; Chinchilla; Electrodes; Locomotion; Reflex, Vestibulo-Ocular; Semicircular Canals;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6090584
