Data-Driven Lung Nodule Models for Robust Nodule Detection in Chest CT

The quality of the lung nodule models determines the success of lung nodule detection. This paper describes aspects of our data-driven approach for modeling lung nodules using the texture and shape properties of real nodules to form an average model template per nodule type. The ELCAP low dose CT (LDCT) scans database is used to create the required statistics for the models based on modern computer vision techniques. These models suit various machine learning approaches for nodule detection including Bayesian methods, SVM and Neural Networks, and computations may be enhanced through genetic algorithms and Adaboost. The eminence of the new nodule models are studied with respect to parametric models showing significant improvements in both sensitivity and specificity.