Title :
Monitoring of living cells adhesion behavior by means of surface plasmon resonance biosensor
Author :
Wang, Chunyan ; Tan, Yingjun ; Yu, Jianru ; Gu, Yin ; Li, Yinghui
Author_Institution :
State Key Lab. of Space Med. Fundamentals & Applic., China Astronaut Res. & Training Center, Beijing, China
Abstract :
Surface plasmon resonance (SPR) sensor provides a useful means to study the concentration change on the sensor chip. In this study, we developed a living cells adhesion behavior monitoring technology, using SPR biosensor to detect the refractive index change induced by the living C6 cells attachment. Combined with the cell images under microscope, the re-distribution of molecules between the cell-matrix during the cell adhesion process was discussed.
Keywords :
adhesion; biosensors; cellular biophysics; molecular biophysics; refractive index; surface plasmon resonance; SPR sensor; cell images; cell-matrix; concentration change; living C6 cells attachment; living cell adhesion behavior monitoring; refractive index change; sensor chip; surface plasmon resonance biosensor; Adhesives; Biosensors; Monitoring; Optical surface waves; Optical waveguides; Plasmons; Surface waves; cells adhesion; dynamic; surface plasmon resonance;
Conference_Titel :
Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on
Conference_Location :
Nanjing
Print_ISBN :
978-1-4244-9172-8
DOI :
10.1109/RSETE.2011.5966155
