Lung segmentation based on Nonnegative Matrix Factorization

In this paper, a new framework for 3D lung segmentation is proposed. The primary step of this framework is to model both the spatial interaction and first-order visual appearance of the lung tissue based on a new Nonnegative Matrix Factorization (NMF) approach that has the ability to handle the inhomogeneity in the lung regions caused by arteries, veins, bronchi, and possible pathological tissues. The performance of our framework is assessed on fourteen 3D CT images. Based on the Dice Similarity Coefficient (DSC), experimental results showed that the proposed approach outperforms other lung segmentation techniques.