DocumentCode :
2482704
Title :
Spectral features of electroencephalogram in characterizing various brain states under anesthesia
Author :
Kang, Eunji E. ; Zalay, Osbert C. ; Beheiry, H.E. ; Wong, Jean ; Campo, Martin Del ; Carlen, Peter L. ; Bardakijan, Berj L.
Author_Institution :
Inst. of Biomater. & Biomed. Eng., Univ. of Toronto, Toronto, ON, Canada
fYear :
2011
fDate :
Aug. 30 2011-Sept. 3 2011
Firstpage :
3099
Lastpage :
3102
Abstract :
The administration of the anesthetic agents is known to alter the electroencephalogram (EEG) signal significantly with the brain being their primary target. In this study, we analyzed the EEG recorded from six ASA I/II patients undergoing a 1-2 hour surgery. The EEG was collected before and during induction, maintenance and recovery of anesthesia using the 10/20 lead-system. A combination of fentanyl and propofol (±rocuronium) was used for induction and a Sevoflurane in air/O2 mixture was administered through an endotracheal tube to achieve the steady minimum alveolar concentration (MAC). This study showed that 0 to 4 Hz signal power was most sensitive to the changes associated with induction of anesthesia whereas the 4 to 12 Hz power was important in classifying states during maintenance of anesthesia. Anesthesia also promoted heightened phase coherence in 8 to 16 Hz and 16 to 30 Hz ranges during maintenance and induction of anesthesia, respectively. Additionally, strong cross-frequency coupling between 7 to 20 Hz and 10 to 40 Hz was observed during anesthesia suggesting alteration of neural coding.
Keywords :
electroencephalography; medical signal processing; surgery; ASA I-II patient; Sevoflurane; air-O2 mixture; anesthesia; brain state; cross-frequency coupling; electroencephalogram; endotracheal tube; fentanyl; frequency 0 Hz to 40 Hz; minimum alveolar concentration; neural coding; phase coherence; propofol; rocuronium; signal power; spectral feature; surgery; time 1 h to 2 h; Anesthesia; Coherence; Couplings; Electrodes; Electroencephalography; Indexes; Maintenance engineering; Anesthesia; Brain; Electroencephalography; Humans;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
ISSN :
1557-170X
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/IEMBS.2011.6090846
Filename :
6090846
Link To Document :
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