DocumentCode :
2491602
Title :
Predicting drug absorption rates through human skin
Author :
Sun, Yi ; Lam, Lun Tak ; Moss, Gary ; Prapopoulou, Maria ; Adams, Rod ; Davey, Neil ; Gray, David ; Brown, Mark
Author_Institution :
Univ. of Hertfordshire, Hatfield, UK
fYear :
2010
fDate :
18-23 July 2010
Firstpage :
1
Lastpage :
5
Abstract :
Predicting the rate at which a substance will pass through human skin and into the bloodstream is a problem of current interest. We use Gaussian Process modeling to train a set of predictors using every combination of six molecular features. We find that only three of the features are needed for our best predictor. This result could be useful in the further analysis of skin permeability.
Keywords :
Gaussian distribution; absorption; biodiffusion; biomedical measurement; drugs; physiological models; skin; Gaussian process; bloodstream; drug absorption rates; human skin; skin permeability; Absorption; Chemicals; Gaussian processes; High definition video; Permeability; Skin; Training;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Neural Networks (IJCNN), The 2010 International Joint Conference on
Conference_Location :
Barcelona
ISSN :
1098-7576
Print_ISBN :
978-1-4244-6916-1
Type :
conf
DOI :
10.1109/IJCNN.2010.5596603
Filename :
5596603
Link To Document :
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