Title :
Modulation of peripheral nerve excitability by high frequency ultrasound
Author :
Phillips, W.B. ; Martineau, R.L. ; Sweeney, J.D. ; Towe, B.C.
Author_Institution :
Dept. of Bioeng., Arizona State Univ., Tempe, AZ, USA
Abstract :
High frequency tone bursts of ultrasound are capable of suppressing and enhancing peripheral nerve action potential events. An in vitro frog sciatic nerve preparation was used as a biological model. The peak intensity of the sound delivered to the nerve was 150-200 W/cm2. Tone bursts consisted of 0.5 to 75 ms pulses delivered at a rate of 1-10 Hz and had center frequencies between 17 and 20 MHz.
Keywords :
bioelectric potentials; biological effects of acoustic radiation; biomedical ultrasonics; neurophysiology; ultrasonic effects; 0.5 to 75 ms; 17 to 20 MHz; biological model; electrical stimulation; high frequency tone bursts; high frequency ultrasound; in vitro frog sciatic nerve preparation; peripheral nerve action potential events; peripheral nerve excitability modulation; Acoustic transducers; Data acquisition; Electrical stimulation; Electrodes; Frequency; Pulse amplifiers; Space vector pulse width modulation; Switches; Ultrasonic imaging; Ultrasonic transducers;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1053189