Title :
Aqueous humor and iris mechanics in synechial closure in primary angle-closure glaucoma
Author :
Huang, E.C. ; Heys, J.J. ; Barocas, V.H.
Author_Institution :
Dept. of Chem. Eng. & Material Sci., Minnesota Univ., Minneapolis, MN, USA
Abstract :
Primary angle-closure glaucoma features a narrow anterior chamber angle in which the anteriorly positioned iris blocks aqueous humor outflow through the trabecular meshwork, subsequently increasing the intraocular pressure. A mathematical model is used to investigate the aqueous humor-iris interaction in synechial angle closure. The model predicted increased intraocular pressure as the anterior chamber angle decreased and a plateau iris configuration in synechial angle closure - consistent with clinical observations.
Keywords :
biomechanics; diseases; eye; physiological models; anterior chamber angle; aqueous humor-iris interaction; clinical observations; eye angle-closure; intraocular pressure; iris mechanics; mathematical model; primary angle-closure glaucoma; synechial closure; Adhesives; Biomedical engineering; Chemical engineering; Cornea; Iris; Lenses; Materials science and technology; Mathematical model; Mathematics; Predictive models;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1053211
