A comprehensive comparison of ML algorithms for gene expression data classification

Nowadays, microarray has become a fairly common tool for simultaneously inspecting the behavior of thousands of genes. Researchers have employed this technique to understand various biological phenomena. One straightforward use of such technology is identifying the class membership of the tissue samples based on their gene expression profiles. This task has been handled by a number of computational methods. In this paper, we provide a comprehensive evaluation of 7 commonly used algorithms over 65 publicly available gene expression datasets. The focus of the study was on comparing the performance of the algorithms in an efficient and sound manner, supporting the prospective users on how to proceed to choose the most adequate classification approach according to their investigation goals.