Technique for Plug Dispersion Compensation In Moving Field Capillary Electrophoresis Application

In the past times moving field in capillary electrophoresis (CE) have been introduced. However these attempts are unsuccessfully because the fluid column in the known electric field area introduces parabolic distortion of the osmotic flow profile, and in this way it introduces sever plug dispersions. This paper introduces a method to utilize the separation efficiency of moving field capillary electrophoresis, without the drawback of severe plug dispersion (99% sample flat profile). Also the voltage is maintained on the low values and the speed of the sample is reduced and the efficiency of the separation is increased.