Title :
A Counting Algorithm for Overlapped Chromosomes
Author_Institution :
Dept. of Comput., North China Inst. of Sci. & Technol., Beijing, China
Abstract :
Counting the total number of chromosomes in each metaphase cell and computing the DNA index can predict the outcome of pediatric patients´ treatment. The primary obstacle affecting the result is how to count the number of chromosomes contained in the overlapped chromosomes. In this paper, a counting algorithm for overlapped chromosomes was presented. In the algorithm, we mainly use ultra erosion and 8-connectivity component-labeling to count the number of chromosomes contained in the overlapped chromosomes. The experiment proves that the number of overlapped chromosomes counted by the this algorithm is similar to the corresponding number.
Keywords :
biocomputing; cellular biophysics; molecular biophysics; paediatrics; 8-connectivity component-labeling; DNA index computing; counting algorithm; metaphase cell; overlapped chromosomes; pediatric patient treatment; ultraerosion; Biological cells; Blood; Cancer; Cells (biology); DNA computing; Histograms; Labeling; Medical treatment; Pediatrics; Qualifications;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5162162
