Virtual experiments for controlling blood glucose level in type I diabetes

Author

Agar, Baris ; Birol, Gulnur ; Cinar, Ali

Author_Institution

Dept. of Chem. & Environ. Eng., Illinois Inst. of Technol., Chicago, IL, USA

Volume

3

fYear

2002

fDate

23-26 Oct. 2002

Firstpage

2609

Abstract

An educational software (GLUCOSIM) is developed for illustrating the dynamics of blood glucose and insulin levels in Type I diabetes patients. This work extends the use or GLUCOSIM to closed-loop control of blood glucose levels with the use of an implantable glucose sensor and an insulin infusion pump. Various control strategies are applied to maintain blood glucose concentration close to natural values (Euglycemia) in Type I diabetic patients.

Keywords

biochemistry; biocontrol; biomedical education; biomedical transducers; blood; diseases; drug delivery systems; medical computing; medical control systems; organic compounds; physiological models; Euglycemia; GLUCOSIM; blood glucose concentration; blood glucose dynamics; blood glucose level control; closed-loop control; control strategies; diabetic patients; educational software; implantable glucose sensor; insulin infusion pump; insulin level dynamics; type I diabetes; Biological system modeling; Blood; Chemical technology; Diabetes; Differential equations; Humans; Insulin; Mathematical model; Sugar; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1053451

Filename

1053451