Title :
Predicting phosphene elicitation in patients with retinal implants: A mathematical study
Author :
Savage, Craig O. ; Grayden, David B. ; Meffin, Hamish ; Burkitt, Anthony N.
Author_Institution :
Dept. of Electr. & Electron. Eng., Univ. of Melbourne, Melbourne, VIC, Australia
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
Single pulse waveforms were considered in a recent model for phosphene elicitation in patients with a retinal prosthesis. Waveforms are constrained to charge-balanced stimuli consisting of a single cathodic and anodic pulse pair. Mathematical models of such stimuli have been constructed and presented based upon patient testimonials. In this work, we derive analytic expressions that may be employed to determine equibrightness levels for different waveforms. We provide an example calculation to show quantitative improvements in stimulation efficiency that are consistent with qualitative findings on waveform effects.
Keywords :
artificial organs; eye; physiological models; charge-balanced stimuli; equibrightness levels; phosphene elicitation; retinal prosthesis; single pulse waveforms; Brightness; Delay; Electrical stimulation; Numerical models; Predictive models; Retina; Visualization; Algorithms; Electric Stimulation; Electrodes; Electrophysiology; Humans; Light; Models, Statistical; Models, Theoretical; Nonlinear Dynamics; Phosphenes; Prostheses and Implants; Retina; Retinal Degeneration; Vision, Ocular;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6091542
