Title :
A method for measuring the accuracy of multi-modal image fusion system for catheter-based cardiac interventions using a novel motion enabled targeting phantom
Author :
Hatt, Charles R. ; Stanton, Douglas ; Parthasarathy, Vijay ; Jain, Ameet K. ; Raval, Amish N.
Author_Institution :
Univ. of Wisconsin, Madison, WI, USA
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
Targeted stem cell therapy offers great potential for the repair of infarcted cardiac tissue following heart attack. Safe delivery of stem-cells via catheter based interventions remains a challenge. A multi-modal image fusion approach has been considered for safe targeting of myocardial infarct border zones. In this paper we present an apparatus and method for measuring the accuracy of catheter-based injections using a multi-modal image fusion system. We also present results of the accuracy of our image fusion system under varying levels of cardio-respiratory motion.
Keywords :
cardiology; catheters; cellular biophysics; image fusion; image motion analysis; image registration; medical image processing; phantoms; cardiorespiratory motion; catheter-based cardiac interventions; infarcted cardiac tissue; motion enabled targeting phantom; multimodal image fusion system; myocardial infarct border zones; targeted stem cell therapy; Accuracy; Catheters; Heart; Image fusion; Phantoms; Sensors; Slabs; Algorithms; Animals; Cardiac Catheterization; Catheterization; Catheters; Equipment Design; Heart; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Spectroscopy; Motion; Myocardial Infarction; Phantoms, Imaging; Polyvinyl Alcohol; Reproducibility of Results; Respiration; Stem Cells; Swine;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6091545