Electrochemical Sensor for Determination of Metallothionein as Biomarker

Author

Blastik, Ondrej ; Hubalek, Jaromir ; Adam, Vojtech ; Prasek, Jan ; Beklova, Miroslava ; Singer, Christoph ; Sures, Bernd ; Trnkova, Libuse ; Zehnalek, Josef ; Kizek, Rene

Author_Institution

Mendel Univ. of Agric. & Forestry, Brno

fYear

2006

fDate

22-25 Oct. 2006

Firstpage

1171

Lastpage

1174

Abstract

Metallothionein (MT) belongs to group of intracellular, high molecular and cysteine-rich proteins. Thanks to its high affinity to heavy metals, the main function of this protein is maintaining homeostasis and detoxification of heavy metals. Thus, this protein is thought to be biomarker of heavy metal pollution. The adsorptive transfer stripping technique in connection with differential pulse voltammetry - Brdicka reaction has been utilized suggesting of sensor for determining of this biomarker.

Keywords

electrochemical sensors; proteins; adsorptive transfer stripping technique; biomarker; cysteine-rich proteins; detoxification; differential pulse voltammetry; electrochemical sensor; heavy metal pollution; high molecular proteins; homeostasis; intracellular proteins; metallothionein; Biochemistry; Biomarkers; Biosensors; Cadmium; Chemical and biological sensors; Chemistry; Organisms; Pollution; Production; Proteins;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2006. 5th IEEE Conference on

Conference_Location

Daegu

ISSN

1930-0395

Print_ISBN

1-4244-0375-8

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2007.355839

Filename

4178834