Title :
Application of Evoked Potential in Acute Stroke in Rats
Author_Institution :
Dept. of Neurology, Central South Univ., Changsha, China
Abstract :
The aim of this paper is to study the characteristic of latency of evoked potential and monitoring brain function following acute ischemic stroke in rats. The model of acute ischemic stroke in rats was made by middle cerebral artery occlusion (MCAO). All animals of ischemic stroke were detected latency of somatosensory evoked potential (SEP) and motor evoked potential (MEP) after different durations of (12 h, 1 d, 3 d), the cerebral blood flow (rCBF) was also measured by hydrogen cleaning method after MCAO, the result were compared with normal control group. The result showed that the latency of positive wave 1 (PI), negative wave 1(N1) and positive wave 2 (P2) waves in SEP were significantly prolonged after MCAO, the level of rCBF was significantly lower than that of previous occlusion. The evoked potential, might be relation to the rCBF, the ischemic stroke could cause prolonged the latency of motor evoked potential waves, evoked potential might be applied to evaluate the ischemic stroke.
Keywords :
bioelectric potentials; blood flow measurement; brain; medical disorders; neurophysiology; somatosensory phenomena; acute ischemic stroke; brain function monitoring; cerebral blood flow; hydrogen cleaning method; middle cerebral artery occlusion; motor evoked potential; somatosensory evoked potential; time 1 d; time 12 h; time 3 d; Animals; Arterial occlusion; Arteries; Blood flow; Delay; Ischemic pain; Magnetic resonance imaging; Patient monitoring; Positron emission tomography; Rats;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5162385
