Comparison for Antitumor Activities of Some Chinese Medicinal Herb Extracts

Author

Juan Li ; Keli Chen ; Binghong Yang ; Xin Yu

Author_Institution

Key Lab. of TCM Resource & TCM Compound, Hubei Coll. of Traditional Chinese Med., Wuhan, China

fYear

2009

fDate

11-13 June 2009

Firstpage

1

Lastpage

3

Abstract

The anti-tumor activities of six medical plants (Herba Scutellariae Barbatae, Herba Lobeliae Chinensis, Herba Duchesneae Indicae, Herba Solani Lyrati, Rhizoma Smilacis Glabrae, Rhizoma Paridis Chinensis), commonly used as antitumor drugs, have been submitted to tests of MTT, Flow cytometry (FCM), DNA laddering analysis and caspase-3 expression using Bel-7402, HT-29 and HeLa cell lines. Total alkaloids and total glycosides extracts from Rhizoma Paridis Chinensis showed stronger action on inhibiting proliferation and inducing apoptosis of tumour cells.

Keywords

biochemistry; biological techniques; botany; cellular biophysics; drugs; tumours; Bel-7402 cell line; Chinese medicinal herb extracts; DNA laddering analysis; Duchesneae indicae; HT-29 cell line; HeLa cell line; Lobeliae chinensis; MTT; Paridis chinensis; Scutellariae barbatae; Smilacis glabrae; Solani lyrati; antitumor activities; antitumor drugs; caspase-3 expression; flow cytometry; total alkaloid extracts; total glycoside extracts; Cancer; Digestive system; Diseases; Drugs; Educational institutions; In vitro; In vivo; Lungs; Medical treatment; Tumors;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on

Conference_Location

Beijing

Print_ISBN

978-1-4244-2901-1

Electronic_ISBN

978-1-4244-2902-8

Type

conf

DOI

10.1109/ICBBE.2009.5162537

Filename

5162537