• DocumentCode
    2505238
  • Title

    Effect of GA3 and S3307 on Content of Taxol and Its´ Precursors of Taxus cuspidate In Vitro

  • Author

    Dong xuehui ; Chen Xiaowen ; Duan liusheng

  • Author_Institution
    Coll. of Agricutural & Biotechnol., China Agric. Univ., Beijing, China
  • fYear
    2009
  • fDate
    11-13 June 2009
  • Firstpage
    1
  • Lastpage
    3
  • Abstract
    Young shoots, collected from about 100 trees, were sprayed on 10 mg/L Sumiseven (S3307) and 100 mg/L Gibberellin (GA3) separately., and investigated for their contents of 10-deacetyl Baccatin III (10-DAB), Baccatin III and Paclitaxel (Taxol) at different time in order to get a better understanding of the synthesis mechanism of taxol in vitro. The result shows that S3307 and GA3 change the metabolism of the three taxanes, and improve the contents of the three taxanes at some degree. We suggest that the effect role occurs before the biosynthesis of 10-DAB.
  • Keywords
    biochemistry; biological techniques; drugs; 10-deacetyl Baccatin III; GA3; S3307; Sumiseven; Taxus cuspidate; gibberellin; taxol; Biochemistry; Biotechnology; In vitro; In vivo; Inhibitors; Methanol; Production; Sampling methods; Solids; Spraying;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
  • Conference_Location
    Beijing
  • Print_ISBN
    978-1-4244-2901-1
  • Electronic_ISBN
    978-1-4244-2902-8
  • Type

    conf

  • DOI
    10.1109/ICBBE.2009.5162695
  • Filename
    5162695
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2505238