Variability of defibrillation threshold in HEARTSIM: a 3D computer model of the heart

Author

Thakor, N. ; Province, R. ; Fishler, M. ; Chen, R.

Author_Institution

Dept. of Biomed. Eng., Johns Hopkins Med. Sch., Baltimore, MD, USA

fYear

1991

fDate

23-26 Sep 1991

Firstpage

209

Lastpage

212

Abstract

The authors present a three-dimensional computer model of the heart to demonstrate simulation of ventricular fibrillation (VF) and defibrillation (DF). Delivery of a run of extra-stimuli initiated self-sustaining rapid regular rhythm or coarse and fine VF. Shocks of increasing strengths were applied at various times to determine the energy required for successful DF. The success rate curve versus DF energy showed the expected sigmoidal shape. For a given episode, the energy required for DF showed remarkable variation from moment to moment. Two successive pulses significantly lowered the energy requirement. The optimum interval between pulses was found to center around 85 ms, and the energy for the second pulse was lower than that for the first pulse. A biphasic pulse also lowered the energy requirement

Keywords

cardiology; digital simulation; medical computing; patient treatment; physiological models; 3D computer heart model; 85 ms; HEARTSIM; biphasic pulse; cardiac simulation; defibrillation threshold variability; energy requirement; optimum interpulse interval; self-sustaining rapid regular rhythm; sigmoidal shape; ventricular fibrillation; Biomedical computing; Computational modeling; Computer simulation; Current density; Defibrillation; Electric shock; Energy states; Heart; Pulse shaping methods; Shape;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1991, Proceedings.

Conference_Location

Venice

Print_ISBN

0-8186-2485-X

Type

conf

DOI

10.1109/CIC.1991.169082

Filename

169082