Title :
Drug-polyester conjugated nanoparticles for cancer drug delivery
Author :
Tong, Rong ; Tang, Li ; Yin, Qian ; Cheng, Jianjun
Author_Institution :
Massachusetts Inst. of Technol., Cambridge, MA, USA
fDate :
Aug. 30 2011-Sept. 3 2011
Abstract :
We report here the synthesis of camptothecin-polylactide conjugate via camptothecin-initiated lactide polymerization and the formation of nanoconjugates for drug delivery applications.
Keywords :
biomedical materials; cancer; drugs; nanomedicine; nanoparticles; polymerisation; camptothecin-initiated lactide polymerization; camptothecin-polylactide conjugate; cancer drug delivery; drug-polyester conjugated nanoparticles; nanoconjugates; Drugs; Loading; Nanoparticles; Plastics; Polymers; Programmable logic arrays; Zinc; Antineoplastic Agents; Camptothecin; Catalysis; Chromatography, High Pressure Liquid; Drug Delivery Systems; Nanoparticles; Neoplasms; Pharmaceutical Preparations; Polyesters; Succinic Anhydrides;
Conference_Titel :
Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4121-1
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2011.6092056
