Frequency-domain analysis of arterial blood pressure: a probe for central nervous system activity

Author

Kresh, J.Y. ; McVey, M.J. ; Frasch, H.F. ; Pelleg, A. ; Brockman, S.K.

Author_Institution

Dept. of Cardiothoracic Surg. & Med., Hahnemann Univ., Philadelphia, PA, USA

fYear

1991

fDate

23-26 Sep 1991

Firstpage

377

Lastpage

380

Abstract

Spontaneous, self-sustained arterial blood pressure oscillations (APO; Mayer-rhythm) were studied in dogs exposed to hypotension, hemorrhage, hypoxia, or cerebral ischemia. Frequency spectra analysis of APO revealed a large amplitude (15-30 mmHg), low frequency (0.04-0.06 Hz) component. Higher frequency peaks (f>0.1 Hz) of much lower power amplitude were associated with respiratory activity. These experimental pathophysiologic states resulted in the loss of broadband frequency spectra (observed in control studies) and the emergence of dominant bifurcating narrowband APO rhythms. The periodicities observed implicate a CNS-mediated neural pacemaker (i.e. sympathetic overdrive) in arterial pressure oscillations

Keywords

haemodynamics; neurophysiology; 0.04 to 0.06 Hz; 15 to 30 mmHg; CNS-mediated neural pacemaker; Mayer-rhythm; arterial blood pressure; arterial pressure oscillations; broadband frequency spectra; central nervous system activity; cerebral ischemia; dogs; experimental pathophysiologic states; frequency-domain analysis; hemorrhage; hypotension; hypoxia; probe; respiratory activity; sympathetic overdrive; Arterial blood pressure; Bifurcation; Dogs; Frequency domain analysis; Hemorrhaging; Ischemic pain; Narrowband; Pacemakers; Probes; Rhythm;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1991, Proceedings.

Conference_Location

Venice

Print_ISBN

0-8186-2485-X

Type

conf

DOI

10.1109/CIC.1991.169123

Filename

169123