Title :
MIGRATION AND PROLIFERATION ANALYSIS FOR BLADDER CANCER CELLS
Author :
Said, Asaad F. ; Karam, Lina J. ; Berens, Michael E. ; Lacroix, Zoé ; Renaut, Rosemary A.
Author_Institution :
Dept. of Electr. Eng., Arizona State Univ., Tempe, AZ
Abstract :
This paper presents a cell evolution analysis (CEA) scheme for bladder cancer cells. The proposed scheme consists of a cell migration analysis component for computing the overall migration rate of the cell cluster, and a cell proliferation analysis component based on counting the individually segmented cells within the cell cluster at different time points. The proposed CEA scheme performs well for images with poor contrast and high cell concentrations, even when the cells are overlapping and small. Results are presented to illustrate the performance of the proposed scheme
Keywords :
biological organs; cancer; cell motility; image segmentation; medical image processing; tracking; bladder cancer cells; cell cluster; cell counting; cell evolution analysis; cell migration analysis; cell migration rate; cell proliferation analysis; high cell concentrations; poor-contrast images; segmented cells; Background noise; Bladder; Cancer; Clustering algorithms; Genomics; Image analysis; Image processing; Image segmentation; Microscopy; Stem cells;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
1-4244-0672-2
Electronic_ISBN :
1-4244-0672-2
DOI :
10.1109/ISBI.2007.356853
