Title :
The Research on the CD138 Immune Magnetic Beads for Multiple Myeloma Cells Sorting
Author :
Zhang, Jijun ; Ma, Xuemei
Author_Institution :
Coll. of Life Sci. & Bio-Eng., Beijing Univ. of Technol., Beijing, China
Abstract :
CD138 immune magnetic beads, made from CD138 antibody and nano-gold magnetic beads, can be used to separate multiple myeloma (MM) cells from others. The enriched MM cells are used for chromosome examination by the way of FISH (fluorescence in situ hybridization), which is important for disease prognosis. Now in domestic it must be imported, and has a high price. We ourselves make CD138 immune magnetic beads, and evaluate sorting efficiency using RPMI-8226 myeloma cell line.
Keywords :
biomagnetism; cancer; cellular biophysics; fluorescence; magnetic particles; nanotechnology; tumours; CD138 immune nanogold magnetic beads; FISH; RPMI-8226 myeloma cell line; chromosome examination; disease prognosis; fluorescence in situ hybridization; multiple myeloma cell sorting; Biological cells; Blood; Cells (biology); Diseases; Educational institutions; Fluorescence; Immune system; Magnetic separation; Marine animals; Sorting;
Conference_Titel :
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2901-1
Electronic_ISBN :
978-1-4244-2902-8
DOI :
10.1109/ICBBE.2009.5163661
