Title :
HIV structural and biothermodynamics databases: a resource for the pharmaceutical and biotechnology industry
Author :
Bhat, Talapady N. ; Tewari, Yadu B. ; Rodriguez, Henry ; Goldberg, Robert N.
Author_Institution :
Biotechnology Div., NIST, Gaithersburg, MD, USA
Abstract :
Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamic data. However, the data are still largely distributed over several public and private archives leading to issues of inadequate interoperability. In order to maximize the investment made in these areas it is necessary to make it widely available to, and easily accessible to continued development and use by a broad community of researchers and industrialists. For this reason, during the last several years we have been working on developing and maintaining two databases; an integrated structural data resource for AIDS (http://xpdh.nist.gov/hivsdb/hivsdb.html) and a biothermodynamic data resource (http://xpdh.nist.gov/enzyme_thermodynamics ).
Keywords :
biology computing; biotechnology; biothermics; enzymes; microorganisms; pharmaceutical industry; thermodynamics; AIDS; HIV structural database; academia investment; biotechnology industry; biothermodynamics database; federal agencies investment; integrated structural data resource; pharmaceutical industry; Acquired immune deficiency syndrome; Bioinformatics; Biotechnology; Chemical compounds; Databases; Drugs; Human immunodeficiency virus; Inhibitors; Pharmaceuticals; Proteins;
Conference_Titel :
Computational Systems Bioinformatics Conference, 2005. Workshops and Poster Abstracts. IEEE
Print_ISBN :
0-7695-2442-7
DOI :
10.1109/CSBW.2005.71