DocumentCode
2530904
Title
Multi-well structure for cell culture on the chemical imaging sensor
Author
Miyamoto, K. ; Wagner, T. ; Schöning, M.J. ; Yoshinobu, T.
Author_Institution
Dept. of Electron. Eng., Tohoku Univ., Sendai, Japan
fYear
2011
fDate
5-9 June 2011
Firstpage
2130
Lastpage
2132
Abstract
We proposed an application to monitor the cellular metabolism using the chemical imaging sensor. We fabricated multi-well structure made of agarose film on sensor surface. As a model of cellular metabolism, urease enzyme was filled in a well. pH change of the well was clearly observed from chemical images. It demonstrated the potential of the combination of the chemical imaging sensor and the multi-well structure.
Keywords
bioMEMS; biochemistry; biosensors; cellular biophysics; electrochemical sensors; enzymes; molecular biophysics; pH; semiconductor devices; agarose film; cell culture multiwell structure; cellular metabolism model; cellular metabolism monitoring; chemical imaging sensor; pH change; sensor surface; urease enzyme; Biochemistry; Chemicals; Films; Imaging; Light sources; Photoconductivity; Semiconductor device measurement; Chemical imaging sensor; cellular metabolism; light-addressable potentiometric sensor and multi-well structure;
fLanguage
English
Publisher
ieee
Conference_Titel
Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International
Conference_Location
Beijing
ISSN
Pending
Print_ISBN
978-1-4577-0157-3
Type
conf
DOI
10.1109/TRANSDUCERS.2011.5969264
Filename
5969264
Link To Document