Title :
Nanoslit biosensor with single-pixel resolved kinetics capability: Finite element method and experimental results
Author :
Leichlé, T. ; Chou, C.F.
Author_Institution :
LAAS, CNRS, Toulouse, France
Abstract :
We have recently presented DNA hybridization experiments suggesting that biofunctionalized nanoslits can be used as (1) ultra-fast biosensors with the ability to observe reaction kinetics at the single-pixel level and (2) biofilters based on molecular affinity [1]. In this paper, we provide simulation results from finite element analysis supporting our experimental observations.
Keywords :
DNA; biochemistry; biosensors; chemical sensors; finite element analysis; molecular biophysics; nanobiotechnology; reaction kinetics; DNA hybridization experiments; biofilters; biofunctionalized nanoslits; experimental analysis; finite element method; molecular affinity; nanoslit biosensor; single pixel level reaction kinetics; single pixel resolved kinetics capability; ultrafast biosensors; Biological system modeling; Biosensors; DNA; Finite element methods; Fluorescence; Kinetic theory; Probes; Biosensor; Filter; Finite element analysis; Nanochannel; Reaction Kinetics;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International
Conference_Location :
Beijing
Print_ISBN :
978-1-4577-0157-3
DOI :
10.1109/TRANSDUCERS.2011.5969343
