Title :
Digital liquid-liquid microextraction
Author :
Hsu, Y.-W. ; Chen, C.-H. ; Fan, S.-K.
Author_Institution :
Dept. of Mech. Eng., Nat. Chiao Tung Univ., Hsinchu, Taiwan
Abstract :
In this paper, we demonstrated the method to control the concentration after liquid-liquid extraction by generating an encapsulated droplet with precisely controlled water to oil volume ratio by merging individually created aqueous and organic droplets through EWOD (electrowetting-on-dielectric) actuation. In addition, the core and shell droplets were separated after the extraction process by applying EWOD and DEP (dielectrophoresis) forces to manipulating aqueous and organic droplets, respectively. Herein, the minimum concentration in the aqueous droplet was 0.001 mM and the minimum organic droplet volume was 2.5 nl.
Keywords :
chemical variables control; drops; electrohydrodynamics; electrophoresis; encapsulation; microfluidics; organic compounds; wetting; EWOD actuation; aqueous droplet; dielectrophoresis force; digital liquid-liquid microextraction; electrowetting on dielectric actuation; encapsulated droplet; liquid-liquid extraction concentration control; organic droplet; shell droplets; water to oil volume ratio; Dielectrophoresis; Electrodes; Fluorescence; Merging; Permittivity; Reservoirs; dielectrophoresis; droplet encapsulation and extraction; electrowetting-on-dielectric;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International
Conference_Location :
Beijing
Print_ISBN :
978-1-4577-0157-3
DOI :
10.1109/TRANSDUCERS.2011.5969426
