Digital liquid-liquid microextraction

Author

Hsu, Y.-W. ; Chen, C.-H. ; Fan, S.-K.

Author_Institution

Dept. of Mech. Eng., Nat. Chiao Tung Univ., Hsinchu, Taiwan

fYear

2011

fDate

5-9 June 2011

Firstpage

1248

Lastpage

1251

Abstract

In this paper, we demonstrated the method to control the concentration after liquid-liquid extraction by generating an encapsulated droplet with precisely controlled water to oil volume ratio by merging individually created aqueous and organic droplets through EWOD (electrowetting-on-dielectric) actuation. In addition, the core and shell droplets were separated after the extraction process by applying EWOD and DEP (dielectrophoresis) forces to manipulating aqueous and organic droplets, respectively. Herein, the minimum concentration in the aqueous droplet was 0.001 mM and the minimum organic droplet volume was 2.5 nl.

Keywords

chemical variables control; drops; electrohydrodynamics; electrophoresis; encapsulation; microfluidics; organic compounds; wetting; EWOD actuation; aqueous droplet; dielectrophoresis force; digital liquid-liquid microextraction; electrowetting on dielectric actuation; encapsulated droplet; liquid-liquid extraction concentration control; organic droplet; shell droplets; water to oil volume ratio; Dielectrophoresis; Electrodes; Fluorescence; Merging; Permittivity; Reservoirs; dielectrophoresis; droplet encapsulation and extraction; electrowetting-on-dielectric;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS), 2011 16th International

Conference_Location

Beijing

ISSN

Pending

Print_ISBN

978-1-4577-0157-3

Type

conf

DOI

10.1109/TRANSDUCERS.2011.5969426

Filename

5969426