Multiplexed protein detection with an array of silicon-on-insulator microring resonators

Author

De Vos, Katrien ; Girones, Jordi ; De Koninck, Yannick ; Schacht, Etienne ; Bienstman, Peter ; Baets, Roel

Author_Institution

Dept .of Electr. & Comput. Eng., Boston Univ., Boston, MA, USA

fYear

2009

fDate

4-8 Oct. 2009

Firstpage

457

Lastpage

458

Abstract

We have demonstrated simultaneous detection of multiple antibodies in a highly specific way with a novel integrated lab-on-a-chip, featuring silicon-on-insulator ring resonators, non-aggressive microfluidics packaging, receptor binding through a thin PEG layer, and camera based parallel readout.

Keywords

biological techniques; lab-on-a-chip; micro-optics; microfluidics; optical resonators; proteins; readout electronics; silicon-on-insulator; PEG layer; camera based parallel readout; integrated lab-on-a-chip; multiple antibodies detection; multiplexed protein detection; nonaggressive microfluidics packaging; receptor binding; silicon-on-insulator microring resonator array; Microfluidics; Optical resonators; Optical ring resonators; Optical sensors; Optical surface waves; Optical waveguides; Proteins; Q factor; Resonance; Silicon on insulator technology; (130.0130) Integrated optics; (230.0230) Optical devices; (280.1415) Biological sensing and sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE

Conference_Location

Belek-Antalya

ISSN

1092-8081

Print_ISBN

978-1-4244-3680-4

Electronic_ISBN

1092-8081

Type

conf

DOI

10.1109/LEOS.2009.5343180

Filename

5343180