DocumentCode
2533923
Title
Fluorescence enhancement on reflecting substrates for microarray applications
Author
Yalçin, Ayça ; Cretich, Marina ; di Carlo, G. ; Sola, Laura ; Monroe, Margo ; Selim Unlu, M. ; Chiari, Marcella
Author_Institution
Dept. of Electr. & Comput. Eng., Boston Univ., Boston, MA, USA
fYear
2009
fDate
4-8 Oct. 2009
Firstpage
465
Lastpage
466
Abstract
In this study, we report on the utilization of layered substrates for increased performance of fluorescent-based detection schemes. Through optimization of layer thicknesses, we demonstrate that enhancement with respect to commonly used microscope slides is achieved for the collected fluorescence signal.
Keywords
biomedical materials; biosensors; fluorescence; lab-on-a-chip; microsensors; optical films; optical sensors; optimisation; patient diagnosis; silicon; silicon compounds; SiO2-Si; fluorescence enhancement; fluorescent-based detection; layer thickness; microarray applications; optimization; reflecting substrates; Application software; Chemistry; Electromagnetic modeling; Fluorescence; Microscopy; Photobleaching; Reproducibility of results; Semiconductor thin films; Silicon; Substrates;
fLanguage
English
Publisher
ieee
Conference_Titel
LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE
Conference_Location
Belek-Antalya
ISSN
1092-8081
Print_ISBN
978-1-4244-3680-4
Electronic_ISBN
1092-8081
Type
conf
DOI
10.1109/LEOS.2009.5343184
Filename
5343184
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