Title :
Photoacoustic tomography: High-resolution imaging of optical contrast in vivo at new depths
Author_Institution :
Dept. of Biomed. Eng., Washington Univ., St. Louis, MO, USA
Abstract :
Existing high-resolution 3D optical imaging cannot provide penetration into biological tissues beyond one transport mean free path (~1 mm in the skin). Photoacoustic tomography, which combines strong optical contrast and high ultrasonic resolution in a single modality, has broken through this fundamental depth limitation.
Keywords :
bio-optics; biological tissues; biomedical optical imaging; biomedical ultrasonics; optical tomography; photoacoustic effect; biological tissues; biomedical ultrasonics; high-resolution 3D optical imaging; mean free path; optical contrast; penetration depth; photoacoustic tomography; Adaptive optics; Biomedical optical imaging; High-resolution imaging; In vivo; Optical imaging; Optical microscopy; Optical scattering; Optical sensors; Tomography; Ultrasonic imaging; Photoacoustic tomography; optical imaging; photoacoustic computed tomography; photoacoustic imaging; photoacoustic microscopy;
Conference_Titel :
LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE
Conference_Location :
Belek-Antalya
Print_ISBN :
978-1-4244-3680-4
Electronic_ISBN :
1092-8081
DOI :
10.1109/LEOS.2009.5343227