Control of drug-carrying magnetobeads by magnetic gradient-fields

Author

Weyh, Thomas ; Seidl, Nicole ; Gleich, Bernhard ; Alexiou, Christoph ; Koch, Martin ; Wolf, Bernhard

Author_Institution

Dept. of Electr. Eng. & Inf. Technol., Technische Univ. Munchen, Munich, Germany

fYear

2004

fDate

16-19 Aug. 2004

Firstpage

477

Lastpage

479

Abstract

Specially customized magnetic nanoparticles can be used as biocompatible carriers for chemotherapeutical agents. An external magnetic field with a well defined field gradient is able to move these particle-drug-complexes to the anatomical area of interest. Thus the drug-dose which is necessary for successful tumor remission can be reduced - less side effects are the consequence. The aim of this project is to optimize the technical and physical parameters concerning magnetostatics and fluidics.

Keywords

biocontrol; biomagnetism; biomedical materials; drug delivery systems; magnetic fluids; magnetic particles; magnetostatics; nanoparticles; nanotechnology; tumours; biocompatible carriers; chemotherapeutical agents; drug carrying magnetobead control; magnetic gradient fields; magnetic nanoparticles; magnetofluidics; magnetostatics; particle drug complexes; physical parameters; tumor remission; Biomedical imaging; Cancer; Drugs; Hydrodynamics; Magnetic fields; Magnetic particles; Magnetostatics; Medical diagnostic imaging; Nanoparticles; Neoplasms;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanotechnology, 2004. 4th IEEE Conference on

Print_ISBN

0-7803-8536-5

Type

conf

DOI

10.1109/NANO.2004.1392391

Filename

1392391