Flexible intravascular thermal sensors to assess atherosclerosis-mediated changes in hemodynamics

Author

Lee, Juhyun ; Jen, Nelson ; Yu, Fei ; Dai, Wangde ; Yu, Hongyu ; Hsiai, Tzung K.

Author_Institution

Dept. of Biomed. Eng. & Cardiovascular Med., Univ. of Southern California, Los Angeles, CA, USA

fYear

2012

fDate

26-31 March 2012

Firstpage

19

Lastpage

19

Abstract

In this study, we introduced an in vivo convective heat transfer-based micro-electromechanical system (MEMS) sensor that measured real-time experimental vascular shear stress values in the aortas of New Zealand White rabbits (n=4). Experiments were performed to measure flow profile changes in response to hyper-cholesterol diet and an irregular tachycardia condition. We have shown that these conditions induce shear stress changes indicative of pre-atherosclerosis regions by the MEMS thermal sensor.

Keywords

biomechanics; biomedical equipment; biothermics; blood flow measurement; blood vessels; diseases; heat transfer; microsensors; shear flow; MEMS thermal sensor; New Zealand White rabbits; aorta; atherosclerosis; convective heat transfer; flow profile; hemodynamics; hypercholesterol diet; intravascular thermal sensor; irregular tachycardia condition; microelectromechanical system sensor; vascular shear stress value; Biomedical measurements; Hemodynamics; Micromechanical devices; Rabbits; Stress; Thermal sensors; Atherosclerosis; CFD; MEMS; shear stress; tachycardia;

fLanguage

English

Publisher

ieee

Conference_Titel

Health Care Exchanges (PAHCE), 2012 Pan American

Conference_Location

Miami, FL

Print_ISBN

978-1-4673-1135-9

Type

conf

DOI

10.1109/PAHCE.2012.6233431

Filename

6233431