The minimum time estimation for initiating tumor-cell attachment

This work presents the first part of a new framework for preventing the tumor-cell of carcinoma in situ transition from one organ to others. Using an ECIS (electric cell-substrate impedance sensing) chip coated with glutaraldehyde (GA)-crosslinked gelatin patterns suitable for cell attachment, the authors monitor the cell adhesion situation not only by optical microscope but also by electrical means. Therefore the authors design an experiment and a microfluidic chip for investigating the relationship between the metastasis and the surface morphology of blood vessels.