High power facilities for electroporation of biological cells in pulsed magnetic fields

Author

Grainys, A. ; Novickij, V. ; Novickij, J. ; Stirke, A. ; Kaseta, V.

Author_Institution

Dept. of Electr. Eng., Vilnius Gediminas Tech. Univ., Vilnius, Lithuania

Volume

2

fYear

2012

fDate

21-23 May 2012

Firstpage

508

Lastpage

511

Abstract

High power pulsed generator for non-contact cell electroporation application in pulsed magnetic fields is presented. Finite element method analysis of the magnetic field and the analysis of the Jurkat T lymphoblasts electroporation experimental data are overviewed. The dependence of cell electroporation efficiency on the structure of the microcoil was acquired experimentally. Possible problems of the technique, further developments and result overview are discussed.

Keywords

bioelectric potentials; biomagnetism; biomembranes; cellular effects of radiation; finite element analysis; magnetic field effects; Jurkat T lymphoblasts; biological cells; cell electroporation efficiency; finite element method analysis; high power pulsed generator; microcoil structure; noncontact cell electroporation application; pulsed magnetic fields; Capacitors; Drug delivery; Electric fields; Generators; Magnetic fields; Thyristors; Windings; drug delivery; microcoil; non-contact electroporation; pulsed magnetic field generator;

fLanguage

English

Publisher

ieee

Conference_Titel

Microwave Radar and Wireless Communications (MIKON), 2012 19th International Conference on

Conference_Location

Warsaw

Print_ISBN

978-1-4577-1435-1

Type

conf

DOI

10.1109/MIKON.2012.6233623

Filename

6233623