Title :
Molecular dynamics simulation of α-syn12 peptide and synphilin-1 protein complex
Author_Institution :
Agronomy Dept., Dezhou Univ., Dezhou, China
Abstract :
The dynamics and structural character of α-syn12 peptide complex with synphilin-1 protein in aqueous solution has been investigated through molecular dynamics simulations by using GROMOS 43A1 force field. The structural character of α-syn12 peptide complex with synphilin-1 protein adopts in water a loop structure.
Keywords :
molecular dynamics method; proteins; α-syn12 peptide; GROMOS 43A1 force field; loop structure; molecular dynamics simulation; structural character; synphilin-1 protein complex; Aggregates; Amino acids; Analytical models; Assembly; Brain modeling; Humans; Parkinson´s disease; Peptides; Proteins; Spine; force field; molecular dynamics simulation; protein complex;
Conference_Titel :
Information Management and Engineering (ICIME), 2010 The 2nd IEEE International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-5263-7
Electronic_ISBN :
978-1-4244-5265-1
DOI :
10.1109/ICIME.2010.5477640
