A novel amperometric sensor readout based on charge measurement by current integration

Author

Wen-Yaw Chung ; Silverio, A.A. ; Zhou Ming-Ying ; Tsai, V.F.S.

Author_Institution

Electron. Eng. Dept., Chung Yuan Christian Univ., Chungli, Taiwan

fYear

2014

fDate

10-12 Dec. 2014

Firstpage

532

Lastpage

535

Abstract

In this paper, a 3-electrode amperometric sensor readout circuit that can be used for multiple electrochemical sensor cells with an embedded integrator for charge determination is presented. The circuit consists of a wide current range amperometric sensor readout circuit that utilizes a PMOS source at the input thereby providing low input impedance. The circuit also has PMOS pass elements for Working Electrode (WE) selection. The front-end is coupled to a current integrator circuit formed by a Second Generation Current Conveyor (CCII) which gives the amount of charge generated over time by the redox reaction. Pre-layout simulations are carried out using HSPICE G2012.06. The circuit was implemented using TSMC 0.35um Mixed Mode CMOS Process.

Keywords

CMOS integrated circuits; amperometric sensors; charge measurement; current conveyors; digital readout; electrochemical electrodes; electrochemical sensors; oxidation; reduction (chemical); HSPICE G2012.06; PMOS pass elements; PMOS source; TSMC; amperometric sensor readout circuit; charge measurement; current integrator circuit; electrochemical sensor cells; embedded integrator; mixed mode CMOS process; redox reaction; second generation current conveyor; size 0.35 mum; working electrode; Amperometric sensors; Biosensors; Electrodes; Immune system; Integrated circuit modeling; Mirrors; Amperometric Sensor Readout; Current Integration; Pass Transistor; Potentiostat; Second Generation Current Conveyor;

fLanguage

English

Publisher

ieee

Conference_Titel

Integrated Circuits (ISIC), 2014 14th International Symposium on

Conference_Location

Singapore

Type

conf

DOI

10.1109/ISICIR.2014.7029463

Filename

7029463