Smart manipulation of multiple bacteria-driven microobjects based on bacterial autonomous movement

Micro/Nano robots have attracted scientific attention to develop novel technologies such as drug delivery systems. Recently, flagellated bacteria have been used as the driving force of microobjects to develop bacteria-driven microrobots. In this paper, we propose a method of smart manipulation of multiple bacteria-driven microobjects with single manipulated guiderobot based on bacterial autonomous movement, named ??SMARTBOT??, for enabling arbitrary and low cost manipulation of multiple bacteria-driven microrobots. We verify the capability of smart manipulation of multiple bacteria-driven microobjects based on bacterial autonomous movement by using micro/nano pipettes instead of a guiderobot. For the fabrication of the guiderobot and the cargo driven by the bacteria, the fabrication of the arbitrarily-shaped microobjects using photo lithography technique is demonstrated. Additionally, we demonstrate the remote control using optical tweezers and driving using flagellated bacteria of the fabricated arbitrarily-shaped microobjects.