• DocumentCode
    2550550
  • Title

    SABRE: A Tool for Stochastic Analysis of Biochemical Reaction Networks

  • Author

    Didier, Frederic ; Henzinger, Thomas A. ; Mateescu, Maria ; Wolf, Verena

  • Author_Institution
    Sch. of Comput. & Commun. Sci., EPFL, Lausanne, Switzerland
  • fYear
    2010
  • fDate
    15-18 Sept. 2010
  • Firstpage
    193
  • Lastpage
    194
  • Abstract
    The importance of stochasticity within biological systems has been shown repeatedly during the last years and has raised the need for efficient stochastic tools. We present SABRE, a tool for stochastic analysis of biochemical reaction networks. SABRE implements fast adaptive uniformization, a direct numerical approximation algorithm for computing transient solutions of biochemical reaction networks. In addition to the stochastic analysis, SABRE may also conduct deterministic analysis.
  • Keywords
    biochemistry; chemistry computing; numerical analysis; stochastic processes; SABRE; biochemical reaction networks; biological systems; fast adaptive uniformization; numerical approximation algorithm; stochastic analysis; Adaptation model; Analytical models; Biological system modeling; Computational modeling; Markov processes; Mathematical model; Markov chains; biochemical reaction networks; population models; systems biology; tool;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Quantitative Evaluation of Systems (QEST), 2010 Seventh International Conference on the
  • Conference_Location
    Williamsburg, VA
  • Print_ISBN
    978-1-4244-8082-1
  • Type

    conf

  • DOI
    10.1109/QEST.2010.33
  • Filename
    5600387