Title :
SABRE: A Tool for Stochastic Analysis of Biochemical Reaction Networks
Author :
Didier, Frederic ; Henzinger, Thomas A. ; Mateescu, Maria ; Wolf, Verena
Author_Institution :
Sch. of Comput. & Commun. Sci., EPFL, Lausanne, Switzerland
Abstract :
The importance of stochasticity within biological systems has been shown repeatedly during the last years and has raised the need for efficient stochastic tools. We present SABRE, a tool for stochastic analysis of biochemical reaction networks. SABRE implements fast adaptive uniformization, a direct numerical approximation algorithm for computing transient solutions of biochemical reaction networks. In addition to the stochastic analysis, SABRE may also conduct deterministic analysis.
Keywords :
biochemistry; chemistry computing; numerical analysis; stochastic processes; SABRE; biochemical reaction networks; biological systems; fast adaptive uniformization; numerical approximation algorithm; stochastic analysis; Adaptation model; Analytical models; Biological system modeling; Computational modeling; Markov processes; Mathematical model; Markov chains; biochemical reaction networks; population models; systems biology; tool;
Conference_Titel :
Quantitative Evaluation of Systems (QEST), 2010 Seventh International Conference on the
Conference_Location :
Williamsburg, VA
Print_ISBN :
978-1-4244-8082-1
DOI :
10.1109/QEST.2010.33
