Optical imaging simulation using GATE

Author

Cuplov, Vesna ; Buvat, I. ; Mesradi, Mohamed ; Pain, Frederic ; Jan, Sen

Author_Institution

Service Hospitalier Frederic Joliot, Commissariat a l´Energie Atomique, Orsay, France

fYear

2012

fDate

Oct. 27 2012-Nov. 3 2012

Firstpage

2614

Lastpage

2617

Abstract

The Geant4 Application for Emission Tomography (GATE) is an advanced opensource software dedicated to Monte-Carlo (MC) simulations in medical imaging involving photon transportation (positron emission tomography, single photon emission computed tomography, computed tomography) and in particle therapy. In this work, we extend GATE to support simulations of optical imaging such as bioluminescence or fluorescence imaging and validate it against the Monte-Carlo for Multi-Layered media simulation tool. A full simulation set-up for molecular optical imaging (bioluminescence or fluorescence) is implemented and 2D images of the light distribution emitted from a phantom is provided through the GATE software.

Keywords

Monte Carlo methods; bioluminescence; biomedical optical imaging; fluorescence; medical computing; phantoms; public domain software; 2D image; GATE software; Geant4 Application for Emission Tomography; Monte-Carlo simulation; advanced opensource software; bioluminescence imaging; fluorescence imaging; light distribution; medical imaging; molecular optical imaging; multilayered media simulation tool; optical imaging simulation; particle therapy; phantom; photon transportation; positron emission tomography; single photon emission computed tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2012 IEEE

Conference_Location

Anaheim, CA

ISSN

1082-3654

Print_ISBN

978-1-4673-2028-3

Type

conf

DOI

10.1109/NSSMIC.2012.6551597

Filename

6551597