Effect of non-thermal plasma on loading of tetracycline combined with plga into titania nanotube

Titania nanotube (TNT) is a tube shaped thin film that is fabricated by process known as the anodization and it has been known to exhibit excellent biocompatibility and high surface-to-volume ratio, which makes it ideal structure as a carrier for drugs. However, drug loading on TNT has been limited by narrow diameter of TNT and to overcome this problem, the present study attempted to determine whether plasma treatment of inner TNT surface enhances its hydrophilicity and resultant drug carrying properties.