DocumentCode :
256765
Title :
Dimensionality Reduction for Prostate Cancer
Author :
Yanhong Huang ; Guirong Weng
Author_Institution :
Sch. of Mech. & Electr. Eng., Soochow Univ., Suzhou, China
Volume :
2
fYear :
2014
fDate :
26-27 Aug. 2014
Firstpage :
262
Lastpage :
265
Abstract :
Oncogene is a kind of inherent genes exists in humans´ cells. It has been recognized as a genetic disease, if the cells activated, it can make a person carcinogenesis. So, the research of digging out the useful information from gene chip is very hot in modern society. The sample size is small, high dimension, nonlinear which causes the ´dimension disaster´, so dimensionality reduction becomes the key point of prostate tumors´ classification. This paper uses Sparse principle component analysis (SPCA), Laplacian Eigenmaps and Generalized Discriminant Analysis (GDA) to classify the prostate tumors, then Support Vector Machine(SVM) is used to classify the data. Due to the experiment data, GDA gets the best result.
Keywords :
cancer; eigenvalues and eigenfunctions; medical diagnostic computing; pattern classification; principal component analysis; support vector machines; tumours; GDA; Laplacian eigenmaps; SPCA; SVM; carcinogenesis; data classification; dimension disaster; dimensionality reduction; gene chip; generalized discriminant analysis; genetic disease; inherent genes; oncogene; prostate cancer; prostate tumor classification; sparse principle component analysis; support vector machine; Accuracy; Equations; Kernel; Laplace equations; Mathematical model; Support vector machines; Vectors; Dimensionality reduction; SVM; classification; prostate cancer;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Intelligent Human-Machine Systems and Cybernetics (IHMSC), 2014 Sixth International Conference on
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4799-4956-4
Type :
conf
DOI :
10.1109/IHMSC.2014.165
Filename :
6911496
Link To Document :
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