DocumentCode
2570903
Title
Model-free analysis of time-dependent single-molecule spectroscopy: Dynamics of biological macromolecules
Author
Welsher, Kevin ; Yang, Haw
Author_Institution
Dept. of Chem., Princeton Univ. Princeton, Princeton, NJ, USA
fYear
2012
fDate
2-5 May 2012
Firstpage
921
Lastpage
923
Abstract
Rigorous and unbiased statistical analysis of single molecule data is now recognized as a crucial component to substantiate any discovery made through such experiments. This presentation summarizes many such tools, and ventures some future directions in the context of the dynamics of biological macromolecules.
Keywords
biological techniques; biomolecular effects of radiation; fluorescence spectroscopy; macromolecules; statistical analysis; biological macromolecule dynamics; model free analysis; single molecule data; statistical analysis; time dependent single molecule spectroscopy; Chemicals; Fluorescence; Molecular biophysics; Proteins; Spectroscopy; Uncertainty; Fisher information; change point; maximum entropy; maximum information; protein dyamics; single-molecule FRET;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on
Conference_Location
Barcelona
ISSN
1945-7928
Print_ISBN
978-1-4577-1857-1
Type
conf
DOI
10.1109/ISBI.2012.6235705
Filename
6235705
Link To Document