DocumentCode
2571270
Title
Effects of time-varying strong magnetic fields on Ca2+ concentration in cultured bovine adrenal chromaffin cells
Author
Park, Ki Ho ; Ikehara, Toshitaka ; Houchi, Hitoshi ; Yamaguchi, Hisao ; Kinouchi, Yohsuke ; Yoshizaki, Kazuo ; Miyamoto, Hiroshi
Author_Institution
Dept. of Electr. & Electron. Eng., Tokushima Univ., Japan
Volume
6
fYear
1998
fDate
29 Oct-1 Nov 1998
Firstpage
3290
Abstract
We tested the effects of time-varying magnetic fields (from 0.07 to 1.7 T) on the transient elevation of intracellular Ca2+ stimulated by bradykinin (BK) in bovine adrenal chromaffin cells. Addition of BK induced the transient increase in intracellular Ca2+ within few minutes, and then decreased. The magnetic field delayed and perfectly suppressed the increase in the absence of external Ca2+. The inhibitory effects were caused by exposure for only 15 minutes at 1.7 T of magnetic flux density. These results suggested that the magnetic field inhibits Ca2+ release from intracellular Ca2+ stores
Keywords
biological effects of fields; biomagnetism; biomembrane transport; cellular effects of radiation; 0.07 to 1.7 T; Ca2+ concentration; Ca2+ release inhibition; bradykinin stimulated; cultured bovine adrenal chromaffin cells; inhibitory effects; ion channels; plasma membrane; time-varying strong magnetic fields; transient elevation; Bovine; Calcium; Cells (biology); Fluids and secretions; Frequency; Glass; Magnetic field measurement; Magnetic fields; Neurons; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE
Conference_Location
Hong Kong
ISSN
1094-687X
Print_ISBN
0-7803-5164-9
Type
conf
DOI
10.1109/IEMBS.1998.746201
Filename
746201
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