Title :
Removal of brain tissue by Tm-fiber laser
Author :
Tunc, Burcu ; Gülsoy, Murat
Author_Institution :
Biyomed. Muhendisligi Enstitusu, Bogazici Univ., Istanbul, Turkey
Abstract :
The aim of the study was to investigate the thermal effects of the 1940-nm Tm-fiber laser on the dead brain tissue. 4-5 mm coronal sections were taken from lamb brains. Tm-fiber laser was applied at the back (cortical) and below the cortex (subcortical) of these slices with 0.5 mm distance. At the beginning of the research in order to find appropriate laser parameter to be compared for 1940-nm Tm-fiber laser, the carbonization and coagulation times of the brain slices were recorded for each power value, both for cortical and subcortical tissue. The appropriate laser parameters for lamb brain tissue were selected according to this study. Lasers were applied in both continuous and pulsed modes. In continuous mode, doses were changed with fixed application time. In pulsed mode, doses were modified with the change in pulse width. The lesions were detected with microscope. The radius of ablation and coagulation for each laser application was recorded. By calculating ablation efficiency (100× ablation/calculation radius) the appropriate laser doses were determined for both cortical and subcortical tissue. The maximum ablation efficiency for cortical tissue in continuous mode was 200 mW and 600 mW and in pulsed mode was 600 mW and for subcortical tissue maximum ablation efficiency was found 600 mW in both continuous mode and pulsed mode.
Keywords :
biological tissues; biothermics; brain; coagulation; fibre lasers; laser ablation; laser applications in medicine; laser modes; Tm-fiber laser; ablation efficiency; carbonization; coagulation; continuous mode; cortical tissue; dead brain tissue; distance 0.5 mm; lamb brains; laser parameters; power 200 mW; power 600 mW; pulse width; pulsed mode; subcortical tissue; thermal effects; wavelength 1940 nm; Brain; Coagulation; Laser ablation; Laser applications; Laser modes; Lesions; Microscopy; Optical pulses; Power lasers; Space vector pulse width modulation;
Conference_Titel :
Biomedical Engineering Meeting (BIYOMUT), 2010 15th National
Conference_Location :
Antalya
Print_ISBN :
978-1-4244-6380-0
DOI :
10.1109/BIYOMUT.2010.5479794