Title :
Effectiveness research of deep brain stimulation operation for patients with Parkinson´s disease based on polar coordination system with varied origin
Author :
Wang, Min ; Wang, Bei ; Zou, Junzhong ; Zhang, Jian ; Nakamura, Masatoshi
Author_Institution :
Dept. of Autom., East China Univ. of Sci. & Technol., Shanghai, China
Abstract :
Parkinson´s disease (PD) is a common disease of central nervous system among the elderly, and its complex symptoms bring up some difficulties for the clinical diagnosis. And Deep Brain Stimulation (DBS) is an effective treatment method for patients with Parkinson´s disease. In this study, a method based on polar coordination system with varied origin was proposed to quantitatively evaluate the availability of DBS operation for patients with Parkinson´s disease. Totally, seven patients with Parkinson´s disease were participated in the spiral drawing experiment and their scores under Unified Parkinson´s disease Rating Scale (UPDRS) were also recorded. According to the characteristics of hand movement in spiral drawing, a set of parameters were defined and calculated before and after DBS operation. Compared with the UPDRS scores, experimental results showed that this method of evaluation was consistent with the clinical diagnosis. The proposed method based on polar coordinate system with varied origin is effective in clinical diagnosis, and it provides a basis for quantitative evaluating the effectiveness of surgery and treatment.
Keywords :
brain; diseases; geriatrics; neurophysiology; patient diagnosis; surgery; DBS operation; UPDRS scores; central nervous system; clinical diagnosis; deep brain stimulation operation; hand movement; polar coordination system; spiral drawing experiment; surgery; unified Parkinson´s disease rating scale; Brain stimulation; Parkinson´s disease; Satellite broadcasting; Spirals; Surgery; Trajectory; Deep brain stimulation operation; Parkinson´s disease; Polar coordinate system with varied origin; Quantitaitive effectiveness evaluation; Unified Parkinson´s Disease Rating Scale;
Conference_Titel :
Biomedical Engineering and Informatics (BMEI), 2011 4th International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-9351-7
DOI :
10.1109/BMEI.2011.6098386